BIOSONIC TOKYOKEISO | Alldatasheet
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MEASUREMENT AND CONTROL OF BIOMEDICINE MANUFACTURING PROCESSES BIOSONIC Single-use ultrasonic flowmeter for liquids OUTLINE BIOSONIC ultrasonic flowmeter is designed for measuring liquid flow rates in biopharmaceutical manufacturing processes. It consists of BS detector and SFC converter. The wetted parts of the detector have biocompatibility (USP Class VI, FDA, BSE/TSE free) using gamma-sterilizable material (PSU) for single-use. Thanks to our unique ultrasonic flow measurement technology developed over the years, BIOSONIC can measure instantaneous and integrated flow rates with high accuracy without affecting liquids that contain cells. The construction is simple and smooth with no moving parts in the detector that would cause stress to liquids, and with no sealing mechanism that would cause liquid components to accumulate and leave residues. The detector cable is detachable and easy to install for single-use.
FEATURES
❑ Materials of wetted parts of the flow detector: Biocompatible (FDA, USP Class VI, no TSE/BS animal derived components), gamma- sterilizable (up to 50 kGy) ❑ Highly clean construction without causing stress to liquids or leaving residues ❑ Wide rangeability BS04SC Range: 0 to 800 mL/min BS04 Range: 0 to 3000 mL/min BS06 Range: 0 to 8000 mL/min BS10 Range: 0 to 20 L/min BS15 Range: 0 to 50 L/min BS20 Range: 0 to 80 L/min ❑ Liquids with kinematic viscosity of as high as 40 mm 2/s can be measured. ❑ Accuracy: Within ±1% of the reading at flow velocity of 1 m/s or more ❑ Adjustment function to offset the effect on the measurement values caused by a change in liquid temperature (optional) ❑ CE marking ❑ All the detectors are calibrated with the actual flow (water) at the time of shipment. ❑ Soundness of the converter can be checked on site by using a simulator (optional).
APPLICATIONS
❑ Noninvasive, highly accurate flow measurement of liquids in biopharmaceutical manufacturing processes ❑ Flow control by combining pumps, control valves, etc. ❑ Installation into single-use kits and systems OPERATING PRINCIPLE The measuring fluid flows into the U-shaped tube, changes direction by 90 degrees twice, and goes out as shown in Figure 1. Two piezoelectric transducers A and B are mounted at both ends of the measuring section. They emit and receive ultrasonic waves alternately and measure the traveling times t A (A to B) and t B (B to A) through the liquid. Without flow, t A is equal to t B. With flow, t A becomes shorter and t B longer in proportion to the flow rate. Thus, calculating tB - tA gives the flow rate of the liquid. t A and tB depend on the size and shape of the tube and liquid viscosity. The actual flow test data are stored in the linearizer in the converter, which enables BIOSONIC to measure flow rates with high accuracy. IN OUT Piezoelectric transducer B Piezoelectric transducer A Travelling time t B Travelling time tA Figure 1 Operating principle
- Measuring fluid : Liquids (without bubbles, no permeating or eroding PSU)
- Fluid temperature : 2 to 60°C
- Ambient temperature : 0 to 50°C
- Fluid pressure : 0 to 0.5 MPa
- Fluid sound speed : 400 to 2500 m/s
- Fluid kinematic velocity : 0.3 to 40 mm2/s
- Process connection : BS04SC 3/8” hose barb fitting BS04 3/8” hose barb fitting BS06 3/8” hose barb fitting BS10 1/2” hose barb fitting BS15 3/4” hose barb fitting BS20 1” hose barb fitting
- Wetted part material : PSU (FDA, USP Class VI, no animal derived components, TSE/BS measures), gamma-sterilizable
- Maximum permissible dose : 50 kGy
- Enclosure classification : IP65 (indoor use)
- Mass : Refer to Table 1.
Table 1. Sensor weight without cables
- Dedicated cable : Coaxial cable × 2
- Cable length : 5 m (standard)
- Flow range : Refer to Table 2.
Table 2. Flow range and connecting tube size
- Accuracy : Refer to Table 3.
Table 3. Accuracy and flow range
- Pressure loss Pressure loss for water (kPa) = C × Q 2 where C: Factor (Refer to Table 4.) Q: Flow rate (L/min)
Table 4. Pressure loss factor
04 SC 4 mm, high accuracy calibration
Please consult for other directions.
- Output 1) Instantaneous flow rate Current output type : 4-20 mA (load resistance: less than 500 Ω) Voltage output type : 0-10 V (special specifications: 0-5 V/1-5 V) (load resistance: 1 MΩ or more) 2) Pulse output Open collector output : Load rating: Within 30 V DC, 20 mA
- Frequency pulse output : Pulse rate up to 1000 Hz at full scale, duty ratio 1 : 1
- Totalizing pulse output : Output flow rate unit pulse Can be set per pulse by combining either of the following multipliers and units : Multiplier : ×0.1, ×1, ×10, ×100 Unit : mL, L, m3
- Fault output : Output when converter or detector is in error NO or NC is selectable, 0 to 1000 Hz 3) Alarm output Open collector (2 points) : Load rating : Within 30 V DC, 20 mA Instantaneous flow rate alarm (max. /min.) and integrated flow rate (A/B) can be used in combination, NO or NC is selectable.
- Display : 16-characters, 2-lines LCD with backlight
- T erminal table : Plug-type screw fastening terminal × 3 (detachable plug-in type)
- Setting : Panel switch × 4
- Communication : RS485 communication (Modbus protocol)
- Parameter setting : Panel switch or communication
- Display content : Instantaneous flow rate, integrated flow rate, status Alarm: Orange LED
- Time constant : 0.5 to 25 seconds
- Low cut-off : 0 to 25% F .S.
- Linearization : Automatic adjustment by kinematic velocity setting. A manual linearizer can be added (up to 20 points, polyline approximation method).
BS□□/SFC4000-EV Single-use ultrasonic flowmeter for liquids TOKYO KEISO CO., LTD. 3
- Power supply/consumption : 24 V DC ±10%
- Current consumption : 110 mA max. (when LCD backlight is on), approx. 200 mA at power-on
- Ambient temperature : 0 to 50°C
- Ambient humidity : 30 to 80% RH (no condensation)
- Installation method : Panel
- Enclosure classification: IP20 (indoor use)
- Material : ABS (black)
- Mass : Approx. 200 g
- Standards ： EMC：EN61326-1, EN61326-2-3 RoHS (2011/65/EU) Model code SFC4000 – EV – □ Description Instantaneous flow rate output 0 4–20 mA 1 0–10 V 2 0–5 V 3 1–5 V DIMENSIONS Detector BS04SC, BS04, BS06 OUT IN 31.9 φ15 φ15 φ24 φ27 φ10.9 φ9.5 φ6.353/8" hose barb 80±1 142 160 The flow direction is indicated at the base of the hose barb. Materials of flow detector No. Parts Material
1 Body PUS
2 Sensor cap PSU
3 BNC connector Nickel plating
4 Connector mold PVC
5 Cable PVC coating
6 Connector cap PP
7 MMCX connector Gold platng
BS□□/SFC4000-EV Single-use ultrasonic flowmeter for liquids 4 TOKYO KEISO CO., LTD. CAUTIONS ON INSTALLATION
- To ensure accurate, stable measurement, do not bend the connecting tube during installation to avoid stress from the piping.
- Install the instrument in a place where no bubbles are contained in the tubing.
- Keep the measuring tube filled with liquid. Although the instrument can be installed with horizontal, vertical, or slanted tubing, it is recommended to select a position for easy self-draining.
- Install a control valve downstream of the instrument, if necessary.
- Install the flow detector and converter away from noise sources such as power relays and solenoid valves.
- Lay the signal cable away from power cables of high voltage or current. DIMENSIONS Detector BS10, BS15, BS20 The cable connector and main-body unit connection are color-coded: "red" for upper /f_low and "black" for lower /f_low. Model Meter size Connecting tube size (Inner diameter) Size (mm) D d1 d2 A B L C E F G BS10 10 mm 1/2" 14.5 12.7 9.5 110±1 176 194 50 100 19.3 32 BS15 15 mm 3/4" 21.7 19.1 14.7 165±2 234 252 68 136 20 32 BS20 20 mm 1" 27.9 25.4 20.3 220±2 294 312 81 162 25 32 Materials of flow detector No. Parts Material
BS□□/SFC4000-EV Single-use ultrasonic flowmeter for liquids TOKYO KEISO CO., LTD. 5 Head Of/f_ice :Shiba Toho Building, 1 – 7 – 24 Shibakoen, Minato-ku, Tokyo 105 – 8558 Tel : +81-3 – 3431 – 1625 (KEY) ; Fax : +81-3 – 3433 – 4922 * Speci/f_ication is subject to change without notice. Upper left: CONNECTOR 2 Terminal No. Terminal name Description
1 PULSE OUT (+) Pulse output2 PULSE OUT (–)
3 ALARM1 OUT (AL1)
Alarm output4 ALARM1 OUT (COM)
5 ALARM2 OUT (AL2)
Upper right: DETECTOR BNC CONN. Terminal Color Polarity Description IN Red Inflow (upstream) Sensor signal inputOUT Black Outflow (downstream) Lower left: CONNECTOR 1 Terminal No. Terminal name Description
1 SOURCE DC24V (+24V) Power supply
24 V DC ±10%2 SOURCE DC24V (0V)
3 SOURCE DC24V (FG) Grounding
4 FLOW OUT (+) Flow rate output5 FLOW OUT (–)
6 RESET IN (+) Totalization reset input7 RESET IN (–)
Lower right: CONNECTOR 3 Terminal No. Terminal name Description
1 RS-485 (+)
RS-485 communication2 RS-485 (–)
3 RS-485 (SG)
Panel thickness : 0.8 to 5 mm 906 (112)Min.70 Min.120 +0.8 +0.6 Panel cutout CONNECTOR 1 DETECTOR BNC CONN. CONNECTOR 3 IN OUT CONNECTOR 2 1 2 3 4 5 1 2 3 4 5 6 7 1 2 3 PULSE OUT ALARM OUT SOURCE
24 V DC FLOW OUT RESET IN RS-485
+ – AL1 COM AL2 TERMINAL ARRANGEMENT DIMENSIONS Converter SFC4000-EV